Interested in starting Tirzepatide injections? Fill out our intake form. Once reviewed we will give you a call to schedule your first appointment.

Tirzepatide Injection (16.6mg/mL) +B12

FDA-approved in March 2022 as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus, Tirzepatide injection is a glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 (GLP-1) receptor agonist.

In Comparative head-to-head trials, Tirzepatide surpassed Semaglutide’s HbA1c reduction by an additional 24%. According to data from Phase III trial results in type 2 diabetic patients, Tirzepatide was non-inferior and was superior to Semaglutide with respect to mean change in HbA1c from baseline 40 weeks.

At all doses, Tirzepatide (5mg, 10mg, 15mg) also outperformed Semaglutide (1mg) in body weight reduction after 40-weeks. At 5mg, up to 80% of users achieved at least 5% (15lb) reduction in body weight; at 10 mg, 45% reached a 10% (20lb) reduction; and at 15mg, up to 36% of users achieved at least 15% (25lb) reduction in body weight compared to Semaglutide users’ 54%, 24%, and 8% respectively.

Weight loss from baseline to after 40 treatment weeks revealed that Tirzepatide (5mg, 10mg, 15mg) offered at least 30%, 60%, and up to 95% greater weight loss, respectively vs. Semaglutide 1mg.

Impact of Tirzepatide

Tirzepatide selectively binds to and activates the GIP and GLP-1 receptors, the targets for native GIP and GLP-1.

As a GIP and GLP-1 receptor agonist, Tirzepatide is a 39-amino-aciddddd modified peptide with a C20 fatty diacid moiety that enables albumin binding and prolongs the half-life.

At therapeutic doses, it acts on the brain and suppresses appetite. Used in conjunction with a healthy diet and exercise, Tirzepatide helps patients adhere to a reduced-calorie diet, enhancing the weight loss process.

Potential Side Effects

The most common side effects include nausea, diarrhea, vomiting, constipation, stomach pain, headache, fatigue, dizziness, bloating, gas, and heartburn: More serious side effects may include:

  • Pancreatitis (inflammation of the pancreas)
  • Gallbladder problems
  • Kidney problems/failure
  • Serious allergic reactions
  • Increased heart rate
  • Depression

Benefits of B12

  • Increased energy
  • Boosted metabolism
  • Enhanced mood
  • Increased memory
  • Enhanced mental clarity and focus

Low energy and feeling sluggish is a common side effect when beginning Tirzepatide injections. It takes time for your body to adjust to the weight loss injections so the combination of B12 helps combat these side effects.